For a session with Activated Air, you breathe air directly from the Activated Air device through a nasal cannula or diffuser. It does not fill the room like a humidifier or air purifier, but rather the Activated Air needs to reach you quickly and be breathed in. The cannula or diffuser attaches to the front of the device. With the cannula, the air is directed to your nose; with the diffuser the air is dispersed just in front of your mouth and nose.

For the ActiveAir 5, the minimum session time is 20 minutes. For the ActiveAir 3 the minimum time is 40 minutes. You can breathe normally during the session; some people do like to take deep breaths as well. You can do anything during your Activated Air session, as long as you can stay connected to the device. Many people sit and read, talk on the phone, or work on their computer. Some people sleep, and others use it while exercising, running on a treadmill, or doing yoga. It is also used in spas and wellness centers while people undergo other services such as massage,  colon hydrotherapy, manicures and pedicures, etc.

It is recommended that you use Activated Air at least 3 times a week. Many people feel so good after using the device they choose to use it every day, and may do longer sessions as well.

According to the American Diabetes Association, 23.6 million children and adults have diabetes in the US. Dr. Martin Silink, the president-elect of the International Diabetes Federation, says ”diabetes is one of the biggest health catastrophes the world has ever seen.” The rate at which the incidence of diabetes is growing is what is causing so much concern. Globally, it has increased from 30 million to 230 million during the last 20 years, according to the International Diabetes Federation. Domestically, the diabetes epidemic is growing by almost 5% a year, according to a study led by Linda S. Geiss, of the Center for Disease Control. “We found that diabetes and obesity are growing together,” Geiss stated, “It has grown for the last 15 years and there is no hint of it slowing down.”

There are several studies which suggest that Oxidative Stress is related to diabetes. Motz and Ceriello (2004) published a paper in the Journal of the American Heart Association called Is Oxidative Stress the Pathogenic Mechanism Underliying Insulin Resistance, Diabetes, and Cardiovascular Disease? The Common Soil Hypothesis Revisited, reviewing the data and studies regarding the topic. They concluded “a puzzle of many pieces of evidence suggests that free radical overgeneration may be considered the key in the generation of insulin resistance, diabetes, and cardiovascular disease.”  An additional concern is that recent research suggests that Diabetes may increase the risk of Alzheimers as reported last week by Lauran Neergaard of the Associated Press. Given that oxidaticve stress damage appears to be a factor in both diseases, this is not surprizing. See Alzheimers Related to Oxidative Stress.

Hans Eng, founder and CEO or Eng3 Corporation, will be speaking to the Arizona Homeopathic and Integrative Medical Association (AHIMA) on Wednesday April 1st in Phoenix Arizona. His presentation entitled The Role of Oxidative Stress in Cellular Activity and Protein Structure Modulation: A state-of-the-art approach for Performance and Health draws on his research which focuses on how to biophysically influence cellular activity, without the use of chemicals or pharmaceuticals. State-of-the-art technology works with the fundamental components that enable cellular activity, including microbiological processes and metabolic operations. Eng3’s technology is implemented where prevention and restoration of the cellular activity is the focus, either for protection, repair or improvement of the entire orchestra of cellular activity or for a particular segment of cellular activities. Eng3’s latest research initiative was done with the University of Indiana, School of Medicine. The resulting publication is available at www.cellscience.com/Reviews19/Redox_signaling.html

Hans Eng

About Hans Eng
Hans-Joachim Eng, Founder and CEO of Eng3 Corporation (www.eng3corp.com)
He holds an advanced degree in Mechanical Engineering and Material Science from the Technical University of Berlin. Before founding Eng3 Corporation, Hans owned and ran a German-based company that designed and produced human implants with a focus on the biophysical optimization to bone and tissue cells. He also managed quality assurance and production for the human implant division at Johnson & Johnson Corporation, and before that at Mecron GmbH.

Meeting details:
AHIMA Meeting
Wednesday April 1st 7:00 pm to 8:30 pm
Moon Valley Country Club
151 West Moon Valley Drive
Phoenix, AZ 85023
Contact Eng3 Corporation at 877.571.9206 for more information

March 21 , 2009 is World Down Syndrome Day and brings our attention to related conditions common in people with Down Syndrome (DS).

Although the cause of Down Syndrome has long been known to be a chromosomal disorder, interesting research is looking at conditions that occur in individuals with Down Syndrome.  Such conditions include the development of Alzheimer like symptoms in their 30’s and 40’s, as well as the fact the “the incidence of autoimmune diseases and cataracts is significantly increased, and the overall ageing process is accelerated.” (Jonavic et al, 1998).

The authors suggest that these conditions are related to high levels of oxidative stress in Down Syndrom patients. After studying 166 subjects they concluded that their “results provide direct evidence for increased oxidative stress in individuals with DS.”

Eng3’s Activated Air device is designed to help cells repair and protect against damage caused by oxidative stress. By supporting the immune system and the body’s natural response to oxidative stress, Eng3’s Activated Air may be a good fit for people with DS.

Biomarkers of oxidative stress are significantly elevated in Down syndrome. Jovanovic S.V., Clements D., MacLeod K., Free Radic Biol Med. 1998 Dec;25(9):1044-8.

During 2008, Eng3 collaborated with the University of Indiana, School of Medicine to create a comprehensive overview of the state of scientific research in protein modulation. This research project produced excellent results including the articulation of connections between different areas of  related science. The reference and introduction to the resulting publication is below.

From redox homeostasis to protein structure modulation and redox signaling therapy

Gabi N. Waite, Dept. of Cellular & Integrative Physiology & Walter X. Balcavage, Dept. of Biochemistry & Molecular Biology , Indiana University School of Medicine, Terre Haute, IN 47809, USA.

Received 29th October © Cell Science 2009

Reactive oxygen species (ROS) have been identified as being responsible for many harmful events in humans, while on the other hand, they are increasingly being recognized as necessary cell signaling agents. The multiple roles of ROS are reflected in the multiple roles of antioxidants, which are part of many disease preventing remedies, but are recently also discussed as disease causing agents. This article provides an overview of the current knowledge of ROS as part of complex redox networks that can harm or benefit cells. It presents up-to-date physicochemical and biological information, in an understandable, novel way, to involve the reader in the significant discussion on ROS and anti-ROS as the novel therapeutic agents of the coming decades.

The whole article is available at: http://www.cellscience.com/Reviews19/Redox_signaling.html

The Centers for Medicare and Medicaid Services, known as CMS, released a report on the state of the US health care system. The current state of health care and, even more importantly the forecasts, make it abundantly clear that individuals should do everything possible to maintain good health. Some of the more interesting data from the CMS report are summarized below.

• The share of the economy devoted to health spending will increase by a percentage point from 2008. This would represent the biggest one-year increase ever recorded – tracking began in 1960
• Overall U.S. health spending in 2009 will hit $2.5 trillion, continuing a trend in recent decades that has seen healthcare encompass an ever-larger proportion of the economy.
• It is projected that the health share of the economy will increase steadily through 2018. By 2018 health spending will be $4.4 trillion and make up 20.3 percent of the overall economy (it is currently $2.5 trillion and consumes 17.6 percent of the economy)
• Spending for private health insurance is slowing as more people lose employer-provided coverage. However private health spending growth is expected to jump from 4.2 percent in 2010 to 6.1 percent by 2018
• Growth in public health spending this year is projected to hit 7.4 percent, amounting to $1.2 trillion. This is largely because Medicaid assistance for the poor is ballooning. Public health spending will surge as the baby boom generation begins entering the Medicare health insurance program for people over 65

The CMS forecast reflect the stark reality of the US health system. Eng3 is doing everything we can to help people avoid the need to rely on it. Healthy aging is certainly the most cost effective way to go. Fortunately a growing number of people are investing in their health and taking preventative measures.

Dr Hekimi and colleague Jeremy Van Raamsdonk of McGill University studied mutant worms after they had progressively disabled five genes responsible for detoxifying ROS. Their results call into question the theory that oxidative stress causes aging. They found that reducing mitochondrial activity by damaging it with ROS did not reduce the life span of worms, and in one case made the worms live longer. While the authors refer to aging, it appears they studied longevity. The authors do not appear to have answered questions about the worms’ health and performance after they were damaged. This is perhaps the most important component of aging. It would be interesting to know if these damaged worms remained healthy or just lived as long (or longer) than their undamaged counterparts.

Since the mitochondria (the powerhouse of the cell) was damaged in the McGill study, the worms may have been alive but not as healthy as they otherwise would have been. Hopefully further study will investigate this and the possibility that damaging mitochondrial function resulted in lower oxygen metabolism and, as a result, actually decreased the kind of damage that would shorten the worm’s life. You may also be interested in Oxygen Ironey* and Healthy Aging and Anti Aging

Health and vitality during later stages of life is a primary reason for people to use Eng3’s Activated Air. Our focus is on the quality of life – helping people stay active, alert and vital as they age.