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Oxidative Stress Relief and Signs of Mild Autism

April 28th, 2009

In 2008 the American Journal of Biochemistry and Biotechnology released a special issue on Autism Spectrum Disorders (Vol 4, No. 2). Many studies in the issue provided evidence to support the concept of oxidative stress in autism. In fact, three separate studies showed increased oxidative damage in brain tissues from autistic subjects. Several articles looked at metal toxicity, including how lead and mercury can induce oxidative stress. A review of two articles also focused on the concept of mitochondrial dysfunction and how this can increase oxidative stress in autism.

The editor, Abha Chauhan writes, “Increased oxidative stress in autism may lead to membrane lipid abnormalities, altered cellular signal transduction, mitochondiral dysfunction, abnormal energy metabolism, excitotoxicity, inflammation and immune dysregulation in autism. These abnormalities may then contribute to abnormal brain development and function resulting in a spectrum of clinical manifestations in autism.”

Research in the field of Autism highlights the complexity of the disease and its treatment. Taking action to reduce oxidative should be a priority because oxidative stress plays a key role in Autism and a myriad of other illnesses. Learn more about this on the Need page.

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Asthma Awareness Month

April 21st, 2009

May is Asthma Awareness Month.  According to the National Heart Lung and Blood Institute, more than 16 million adults and 6 million children in the US are known to have asthma, a chronic lung disease characterized by inflamed and narrowed airways. Many people with asthma suffer with periods of wheezing, shortness of breath, coughing, and chest tightness. Severe asthma attacks may require emergency treatment and can cause death. In fact, it is estimated that there are 5,000 deaths per year related to asthma.

Currently, most options for asthma sufferers involve avoiding triggers in the environment, and quick acting and/or long term medications. Interestingly, an article by K. Ramanujan published at Cornell University (2006) reviewed research conducted at Cornell and Stanford which estimated that 4,000 out of the 5,000 deaths per year related to asthma are actually caused by a specific type of long acting asthma medication. There is obviously a great need for alternatives to asthma medication.

Please view Eng3’s Blog: Asthma Research to read a recent article on oxidative stress related to asthma.

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Pollution and Oxidative Stress-Induced DNA Damage

April 15th, 2009

Danish scientists have shown that particulate air pollution increases oxidative stress-induced DNA damage. Their investigation concludes that “Oxidative stress-induced DNA damage appears to an important mechanism of action of urban particulate air pollution.” The authors also state that “Exposure to ambient air particulate matter (PM) is associated with pulmonary and cardiovascular diseases and cancer.”*

Common sense tells us that air pollution is not good for us. However, these authors identify a number of ways that reactive oxygen species can be generated by particulate air pollution, which leads to oxidative stress damage. The Danish team found overwhelming evidence, based on three different types of experiments, that exposure to diesel exhaust and diesel exhaust particles causes oxidative DNA damage.

Unfortunately much of the world’s population already lives in a polluted environment and we are seeing the results show up in the rise of oxidative stress-related diseases. A previous post discusses the remarkable increase in chronic diseases. Read more about oxidative stress- related diseases at Eng3’s Need page.

*Oxidative stress-induced DNA damage by particulate air pollution.
Risom L, Møller P, Loft S. Institute of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014 Copenhagen K, Denmark.

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Sleep Apnea Treatment and Activated Air by Eng3

April 7th, 2009

Sleep Apnea (or Sleep Apnoea), a condition where people stop breathing for periods of 10 seconds or longer while sleeping, affects up to 18 million people in the US. Interference in breathing reduces the amount of oxygen in the blood. Eventually this lack of oxygen triggers the lungs to suck in air, causing gasping or snorting, and for the person to move to a lighter stage of sleep, or sometimes to wake up.

Sleep apnea is associated with serious heart and circulatory problems including hypertension (high blood pressure) and heart disease, as well as asthma, diabetes, kidney failure, peripheral nerve damage, seizures, epilepsy, and other nerve disorders.

Adults suffering from sleep apnea may experience excessive daytime sleepiness, headaches, irritability, reduced concentration and impaired mental/emotional functioning. Essentially they are not getting deep, restful sleep and enough oxygen at night, which has significant effect on mental and emotional wellbeing, and health.

People who suffer from sleep apnea use Eng3’s device for several reasons:

1) At the cellular level, Eng3 technology is improving cell metabolism so cells utilize oxygen better. When using Eng3 technology, those who suffer from sleep apnea will be using oxygen better both while awake and while sleeping.

2) Improved cell metabolism and oxygen utilization contributes to improved concentration during the day and better sleep at night.

You may be interested in a study on Sleep Apnea done with our technology by Marion Burmann-Urbanek, M.D., and Hendrik Straube, M.D. Learn more about the physical symptoms of anxiety and stress and sleep apnea treatment with Activated Air.

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