The mechanism of how oxidative stress causes damage and its underlying role in aging is documented in many studies. The medical implications of damage that leads to chronic disorders are increasingly being published and can be found when searching: oxidative stress “disease name” (ex: oxidative stress asthma).
In biophysics and cell-biology the process that involves proteins to protect against oxidative stress damage is known as oxidative response. The fact is that oxidative stress damages proteins and damaged proteins have a diminished repair capability.
This important repair mechanism for RNA and DNA is described in detail in the Journal of Biomedicine and Biotechnology: Oxidative Damage to RNA in Neurodegenerative Diseases
Nunomura et al. describe the importance of the repair mechanism for RNA. If the repair mechanism is diminished it can lead to neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, Down syndrome, Dementia with Lewy Bodies, and Prion disease. In detail they explain the involvement of proteins in enzymatic reactions that are responsible for protection against oxidative stress and summarize it:
“Furthermore, cells have mechanism of dealing with nucleotide damage other than direct repair, which seems to be useful for defense against oxidative damage to both DNA and RNA.”
At ENG3 Corporation, our focus is to design devices that improve oxidative response. A biophysical treatment is available with Eng3’s technology, which is drug-free and extremely easy to use. Addressing protein structure is being implemented in medical clinics, medi-spas and wellness centers. Home users are also using it to address age-related disorders and as a breakthrough prevention tool.